Doctor, what is the difference of the methods and treatments you apply differently from other treatments, so that you have a higher success rate in your cases? We can answer questions such as…
Firstly, we do not encourage our patients to TESE without question. This is already a very serious problem in itself.
We are still witnessing the persistence of the same mistake. There should be a question, “What are you doing?
We look at the risk analysis before the treatment and the stage of the disease. In other words, when we say we treat, we treat correctly. Because when we treat a case, we carry out a follow-up by putting forward a correct procedure, and I regret to express that such a method is unfortunately not applied anywhere else except us. One of these steps is to monitor hormones with blood tests. Another step is to follow the course of sperm germ precursor cell analysis.
Secondly, there are four steps in the correct treatment and some mistakes continue to be made here. The first of these is the spermatocyte exit stage from the stem cell, the second is the return stage of the spermatocyte to the spermatid, the third is the problems in the transition of the spermatid entering the acrosomal effect to the FSH receptor formation stage, and the fourth is the main problem we call the maturation problem of spermatid.
We overcome the first three problems, there is no problem so far.
Not every case can pass to the last stage. The subject is a genetic-based subject that is related to many reasons and requires a high level of effort, but we often see that extreme mistakes are made even in these first three stages. Such as giving the patient Pregnyl etc. together with Clomene.
It’s like adding FSH-based injections to Pregnyl (HCG)-based treatment at the same time when there are no Sertoli cells, i.e. no germ cells.
“Good news! We are calling on behalf of the Ministry of Health and we will take you for stem cell treatment.”
How should we explain the rationale for performing TESE when there are no haploid cells while following the patient with the sperm FISH test, which is not approved by the FDA on the grounds that the success of finding sperm in TESE will increase as the rate of spermatids entering the haploidisation process increases, and which we have been subjected to criticism for being used in vain because it is used outside its purpose and has received objections from many scientific circles today?
What should we say to those who recommend cures such as figs, chickpeas and carob, which have the opposite effect on this issue while receiving HCG-based treatment?
We do not have any problems in treatment in all three stages. We act according to the highest stage in the patient elonge steps that we take from Sertoli only cell level. A study conducted at the University of Padova showed that TESE success increased in treated and predicted cases.
