In my previous articles, I have mentioned that there are some familial cases of genetic inheritance. One of these families is the three siblings…
Afterwards, the second brother and then the youngest one, Ahmet, came.
Due to the age and TESE of the older brother, we observed the development of the transition from no germ cell, that is, only Sertoli cell table (Sertoli Only Cell), from the most backward point to mature sperm with the detailed sperm stem precursor cell analysis we have developed.
Here, we come to the conclusion that if the last 3-4 analyses give the same findings, then we offer two options to the patient after saying that we can only target this much in detail that we can see in semen.
Either we will try in vitro fertilisation with Spermatid with non-surgical or surgical microinjection method, or if we find sperm in TESE, we will try with it. Brother is like this, the other brother is still new, his treatment is ongoing. Progress is slow. Because he developed resistance, we were able to fix it recently. He is one of the TESE ones.
Let’s talk about the little brother. Ahmet has only been with us for a year. His younger age and the absence of TESE was his advantage. While we were going to see if he had reached the beginning of the tail development stage from centriole in the spermiogram, which is our FSH addition criterion, which we call the second stage, we were given the opportunity to see 150-200 sperms as a requirement of his treatment and testicular reserve capacity, without the need to pellet 150-200 sperms (if we cannot find them in the floating liquid, centrifugation, the possibility of seeing those that settle to the bottom more easily, but the method in which it is difficult to use what is found), 1-2 sperms in each field and motile.
>Now, let us contemplate from the beginning to the end and accept our share of what the story is telling us. When we think about how it would be if the brothers, who are exemplary cases of the same genetic structure, were treated without TESE, the answer is ready at the bottom;
If it comes out, it is already OK. If it does not come out in normal semen, it is more certain that there is more chance in surgery.
We do not delay the patient, on the contrary, we follow up until the justification occurs. If he responded to the treatment, we say that he did, if he did not, we return to the beginning with a big session and draw a picture of where we have come from and we make a decision together.
We observe that six months or one year of treatment is usually not enough and that the first positive results usually start after a period of one and a half years on average.
I am perhaps the first person who has made you aware of the fact that TESE is not the right approach in a hasty manner.
Of course we are not against TESE. We believe that untreated, random, unpredictable and unjustified TESE approaches are not correct and we always try to put forward the truths we believe in every environment. Let’s leave aside the natural sperm output in those without TESE, we have experienced spontaneous natural pregnancies. At least we have experienced a happy development in the trial steps without TESE in the name of in vitro fertilisation with spermatid injection. This was the first time.
Because the world knew that this would be tried after TESE and enzymatic sperm extraction. Moreover, our rates of reaching this type of cell development stage are around 90 per cent.
In other words, the patient can now come from 0 stem cells to this stage.
Thanks to what?
With the right treatment, the right phytotherapy…
By sharing such case articles with you, I do not want it to be understood as if we are only calling you to come to us. Until today, I have shared my experiences and treatment methods with you through such articles and I continue to do so.
Some institutions or organisations organise conferences. I am in such a session, and all five of the five cases they presented in their presentations are the success of IVF in patients with natural sperm output whose treatment was carried out by me.
The excuse for not even presenting my name is ready. They say, “We do not act as a sponsor of a certain group.”
Conferences are being held again… For the first time in the world, it was our treatment methods that provided pregnancy with spermatids without TESE.
According to them, the person/persons who provide this are the embryologists and hospitals we send. Let alone inviting them, it is said that those who are at peace with our name should cut their relations with the groups.
While a hospital should firstly inform me after such a success, their endeavours to bring the patient to the media is nothing but a case of documenting their theft while showing bravery.
In Turkish, we express this situation as follows: “Yiğidir öldür but don’t take credit for it!”
I was the first one to explain the ROSI technique when Atsushi Tanaka published it in November 2015. Neither those I have mentioned nor other professionals have understood what Tanaka meant. The world was already achieving pregnancy success by microinjection of the cell obtained by TESE surgery with Elonge Spermatid. Recently, he announced that he did this study on what we should do in cases that do not even have elongated spermatids and that he explained the principles of recognising which cells in the background and in a lower chance position are the cells that can pass to the next stage, and announced that the procedure was performed with 734 eggs and resulted in 14 healthy babies. So it will be necessary to experiment often.
In my opinion, state support for azoospermia is a must. Unfortunately, not everyone has the power to lift the financial burden on this issue. We have done our part as much as we can and we continue to do so.
The patient ratio that we have developed from Sertoli Cell Only level and raised to the advanced levels of Elonge Spermatids is the best world ratio!
So we have more lucky cells than ROSI.
We are in correspondence with the world’s best stem cell autologists about our success! The patent application has been filed.
Let’s say good luck!
