ROSI (Round Spermatid Injection) means in vitro fertilisation with round spermatids.
Remember, for the first time in the world, we started the trials using semen from the semen of a man with our patients in Turkey. After 16 trials, such a pregnancy was obtained in the wife of one of our patients and this was a first in the world.
Now read these lines carefully.
At the end of the 90s, after two researchers named Tesarik and Mendosa published that in vitro fertilisation was performed with elonge spermatid, which is a more advanced series than ROSI, and a healthy birth was achieved, although many trials were made in the world and even in our country, for some reason, no results were obtained.
As of December 2015, the Japanese scientist Tanaka and his team published that 14 healthy babies were brought into the world after 734 trials in the trial of this work with round spermatid, which is one behind the elonge spermatid, which has been achieved in a very small number of successes, and explained the points they complied with in the road map leading to this success.
Since 2012, it is already known that we have been following up patients with the detailed sperm germ precursor cell analysis system, which is the main element of our patient follow-up system. It is obvious how accurate and real the system is, which we follow up with regular checks every three months.
We have developed this system together with embryologist friends. We have made some arrangements on the so-called stained spermiogram method, which is known as such, in accordance with the monitoring of patient results. The patent belongs to us.
I was extremely offended by the approach of the hospital, which crowned this success, which was achieved with our system and which we developed with the correct endocrine and phytotherapy principles, with in vitro fertilisation, by promoting it as their own success without mentioning our name, which is not in accordance with ethical and moral principles, and their efforts to carry the news of this patient to the media and social media.
First of all, the event in this patient is not ROSI, but ELSI or ELOSI, that is, a system in which success is achieved with elonge. Do not be deceived by the perception that success is higher in ROSI. Because in many of our follow-up friends, the ROSI stage has already been completed and we have already reached these target values in many cases with more advanced elonge series and cell-oriented search and scanning in the genetic structure closest to the sperm where the acrosomal appearance is located.
In other words, the disappointment caused by the understanding of the urologist who performs TESE will not be beyond the deception and deception of the untreated and unpredictable patients with the understanding that we are the only hospital that performs ROSI. Unfortunately, it is a separate ethical violation to try to gain patients with the deception that 500 babies were born with ROSI and to give IVF promotions under the pretext of seminar information.
Undoubtedly, the efforts to gain patients for the second trial by saying that they talked and discussed with me also show their character mirrors. Frankly, I did not expect this much.
There were three indispensable conditions for this work;
First, embryologists will be in dialogue.
Secondly, when each case came, I would definitely coordinate the system to avoid any mistakes and most importantly,
In the third stage, we required PGD-NGS testing of all embryos created.
Unfortunately, patients were deceived with pictures of embryos two or three days old without this test. The surplus mate eggs were also wasted!
So, what is the right thing to do?
At the last IVF congress, the path followed by Tanaka and his team in Japan was adopted. In other words, he first suggested freezing women’s eggs early. Afterwards, the samples to be taken from men will be taken first for spermatid genetics, and then a piece of the embryo that has survived until the fifth day of embryo formation (the process of taking a piece of cell with trophoectodermia), and the embryo that is found to be a healthy embryo by PGD-NGS test will be stored for transfer and the principle will be to transfer it to the woman at the appropriate time.
In the past, genetic diagnosis was based on the determination of a few somatic chromosomes and sex chromosomes. Today, we are in the age of genetics and all 22 body chromosomes and sex chromosomes are also scanned. So even the sex is essentially determined. Remember, even in oligospermic and repeatedly unsuccessful embryo transfers, we had pregnancies that we achieved with the PGD-NGS condition, which is now certain to be very important for azoospermia if it is healthy only in this way.
At the moment, we act on this principle in our system and we do not perform ELOSI without researching and examining the cell with the appropriate structure and genetics. We have nothing to do with ROSI. Because ROSI is a more advanced system and almost all of our patients have reached this point. Our aim of acting more carefully is to help our patients both in terms of success-oriented understanding and cost.
In other words, while you are sitting at home, we will be patient until the moment when a voice on the phone says, “Good news, there is a healthy embryo and come here, God willing, the time is that time”. The deceiver is deceived. If you do not do everything right, success will fail.
